This clinical manual, a product of worldwide collaboration among experts in the field of implant dentistry, details the surgical and prosthetic prerequisites for clinicians who wish to apply this treatment protocol in qualified patients. Within the context of biologic and biomechanical principles, the authors provide guidelines for applying this protocol in edentulous and partially edentulous patients in both the mandible and maxilla. This clinically oriented manual also addresses questions such as when to use screw-retained or cement-retained provisionals, how to prepare the prosthesis hairside, and when to have the prosthesis prepared in the